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Table 1 Characteristics of all participants

From: Altered serum levels of IL-33 in patients with advanced systolic chronic heart failure: correlation with oxidative stress

 

HC

non-CHF

CHF

P *

 

n = 177

n = 175

n = 191

 

Age (years)

66.72 ± 5.73

66.98 ± 6.32

66.35 ± 5.91

0.60

Male (%)

102 (57.62%)

101 (57.71%)

109 (57.07%)

0.99

HR (beat/min)

78.46 ± 11.22

81.30 ± 14.58

72.17 ± 16.94

<0.01

SBP (mmHg)

115.10 ± 14.97

136.98 ± 29.04

127.74 ± 23.46

<0.01

DBP (mmHg)

71.97 ± 9.48

76.34 ± 11.96

71.01 ± 15.90

<0.01

Echocardiographic parameters

    

LVEF (%)

NR

68.12 ± 7.14

27. 90 ± 4.09

<0.01

LVEDD (mm)

NR

47.60 ± 3.44

59.07 ± 5.82

<0.01

LVESD (mm)

NR

29.04 ± 3.16

37.88 ± 4.14

<0.01

Primary cardiac diseases

    

CHD (%)

NR

103 (58.86)

103 (53.93)

<0.01

HBP (%)

NR

41 (23.43)

39 (20.42)

 

CHD+HBP (%)

NR

31 (17.71)

35 (18.32)

 

DCM (%)

NR

0 (0)

14 (7.33)

 

Chemical markers

    

serum creatinine (μmol/)

NR

73.48 ± 5.04

130.58 ± 84.50

<0.01

NT-proBNP (ρg/ml)

NR

88.89 (7.14-311.89)

5492.06 (187.21-18199.75)

<0.01

eSOD (U/mg Hb)

NR

1.41 ± 0.77

2.27 ± 1.11

<0.01

MDA (nmol/l)

NR

4.11 ± 1.25

4.69 ± 1.97

<0.01

  1. Continuous data are the mean ± SD or median and range (for NT-proBNP). Categorical variables are presented as absolute and relative frequencies.
  2. *, For categorical data, P values were derived by Pearson’s χ2 test; for continuous data, P values were calculated using the one-way ANOVA except in relation to NT-proBNP, for which the Kruskal-Wallis test was used.
  3. NR, not relevant; HC, healthy controls; CHF, chronic heart failure; CHD, coronary heart disease; HBP, hypertension; DCM, dilated cardiomyopathy; HR, heart rate; SBP, systolic blood pressure; DBP, diastolic blood pressure; LVEF, left ventricular ejection fraction; LVEDD, left ventricular end-diastolic dimension; LVESD, left ventricular end-systolic dimension; NT-proBNP, N-terminal probrain natriuretic peptide; eSOD, erythrocyte superoxide dismutase; MDA, malondialdehyde.