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Table 3 Statistically significant genes by t-test down-regulated vs. HuURNA among examined cells. p < 0.01 (≤, ≥), p < 0.05 (<, >)

From: JAK-STAT and AKT pathway-coupled genes in erythroid progenitor cells through ontogeny

Gene Name

Description vs.

F

F

F

C

C

B

C

B

P

B

P

P

ADRB3

adrenergic, β-3-, receptor

    

<

 

ATP6C

ATPase, H + transporting, lysosomal 16kD

<

   

>

 

BTBD10

BTB (POZ) domain containing 10

 

≤

    

BTRC

beta-transducin repeat containing

     

>

CABP2

Calcium binding protein 2

     

>

CLEC4E

C-type lectin domain family 4, member E

 

≥

≥

  

>

COQ10B

coenzyme Q10 homolog B (S. cerevisiae)

   

<

 

≥

DVL3

dishevelled, dsh homolog 3

   

<

  

F2R

coagulation factor II (thrombin) receptor

    

>

 

FPR1

N-formylpeptide receptor fMLP-R98 ORF

  

>

   

GSTM1

glutathione S-transferase mu 1

  

>

   

IGFBP7

insulin-like growth factor binding protein 7

  

≥

 

>

>

MINK1

Misshapen-like kinase 1 (zebrafish)

  

<

   

MT1A

metallothionein 1A

<

     

NPIPL3

nuclear pore complex interact. protein-like 3

  

<

   

PDGFRA

platelet-derived growth factor receptor, α

   

<

 

>

PDLIM1

PDZ and LIM domain 1

<

  

≥

>

 

PHLDA1

pleckstrin homology-like domain family A m1

    

>

 

PSMC4

proteasome (prosome) 26 S sub, ATPase, 4

   

>

  

SP2

Sp2 transcription factor

 

>

>

   

SQSTM1

sequestosome 1

  

<

 

<

 

ST3GAL1

ST3 β-galactoside α-2,3-sialyltransferase 1

   

<

  

TIMP3

TIMP metallopeptidase inhibitor 3

>

>

>

 

>

 

UBE2D3

ubiquitin-conjugating enzyme E2D 3

 

<

    

UBXN1

UBX domain protein 1

     

<

VAT1

vesicle amine transport protein 1 homolog

  

>

  

>

  1. nuclear gene encoding mitochondrial protein (ngemp), member (m). Bolded genes – expression >1.5 fold vs. HuURNA. F-fetal liver, C-cord blood, B-bone marrow, P-peripheral blood.