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Figure 4 | Journal of Translational Medicine

Figure 4

From: Coculture with hematopoietic stem cells protects cardiomyocytes against apoptosis via paracrine activation of AKT

Figure 4

demonstrates that coculture with NRVCM leads to overexpression of antiapoptotic factors in hematopoietic SC. (a) CCL-12, FN-1, GJA-5 and MIF mRNAs are upregulated in cocultured hematopoietic SC (n = 8). Levels of significance *p < 0.05, ** p < 0.01, *** p < 0.001. (b) ELISA from concentrated cell culture supernatants show higher CCL-12 levels in coculture supernatants compared to monoculture supernatants (n = 3). Level of significance *p < 0.05.

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