Figure 5From: Racial differences in B cell receptor signaling pathway activationIgD+ B cell percentage vs. percentage of anti-IgD responsive (p-S6 “high”) B cells. Anti-IgD-induced p-S6 histograms are shown for 2 representative donors. p-S6 “high” and p-S6 “low” regions were established by estimating the location of the trough in the bimodal profile for one donor and the same regions were applied to all donors. The percentage of anti-IgD induced p-S6 “high” B cells had a statistically significant race-associated difference (p = 0.016, Wilcoxon test). The ratio of the MFI in the p-S6 “high” region to the MFI in the p-S6 “low” region did not differ between the races (p = 0.905, Wilcoxon test).Back to article page