Figure 6
From: Expression of AEG-1 mRNA and protein in colorectal cancer patients and colon cancer cell lines
AEG-1 mRNA and protein expression in the primary tumour compared to tumour stage. (A) AEG-1 mRNA expression was significantly higher in stage I compared to stage III. (B) AEG-1 protein expression in the cytoplasm was similar in stage I and stage II whereas both stages showed a higher staining than stage III (stage I vs. stage II p = 0.88; stage I vs. stage III p = 0.051; stage II vs. stage III p = 0.03), whereas stage III showed a lower staining compared to stage IV (p = 0.002). (C) AEG-1 protein staining in the nucleus decreased from stage I to stage III (stage I vs. stage II p = 0.61; stage I vs. stage III p = 0.048; stage II vs. stage III p = 0.059), whereas stage III showed a lower staining compared to stage IV (p = 0.0026).