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Table 3 Multivariate analysis of overall and disease-free survival rates of HCC patients

From: Decreased expression of zinc-alpha2-glycoprotein in hepatocellular carcinoma associates with poor prognosis

Variable

β

SE

Hazard ratio (95%CI)

P value

Overall sruvival

    

Clinical stage

1.382

0.468

3.982 (1.590-9.974)

0.003

Vascular invasion

0.895

0.258

2.448 (1.477-4.059)

0.001

AFP

0.781

0.273

2.184 (1.279-3.730)

0.004

Tumor differentiation

0.599

0.299

0.550 (0.306-0.988)

0.045

Tumor multiplicity

0.438

0.283

1.549 (0.889-2.698)

0.122

AZGP1

-0.321

0.231

0.725 (0.461-1.141)

0.164

Tumor size

0.319

0.245

1.376 (0.852-2.224)

0.192

Disease-free survival

    

Relapse

1.252

0.167

3.499 (2.522-4.854)

< 0.001

Vascular invasion

0.775

0.206

2.171 (1.449-3.253)

< 0.001

AFP

0.533

0.173

1.705 (1.215-2.392)

0.002

Tumor differentiation

0.521

0.232

0.594 (0.377-0.936)

0.025

Tumor size

0.361

0.18

1.435 (1.009-2.041)

0.044

Tumor multiplicity

0.427

0.238

1.533 (0.962-2.443)

0.072

AZGP1

-0.211

0.166

0.810 (0.585-1.121)

0.204

Clinical stage

0.188

0.286

1.207 (0.689-2.115)

0.510

  1. β, Regression coefficient; SE, standard error; CI, confidence interval; AFP, alpha-fetoprotein; AZGP1, zinc-alpha2-glycoprotein.