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Table 2 Univariate analysis of different prognostic factors in 246 HCC patients

From: Decreased expression of zinc-alpha2-glycoprotein in hepatocellular carcinoma associates with poor prognosis

Variable

Overall survival rate (%)

Disease-free survival rate (%)

 

HR (95% CI)

P value

HR (95% CI)

P value

Age (years)

1.037(0.674-1.596)

0.867

1.120(0.816-1.539)

0.482

Gender

0.74(0.356-1.536)

0.419

1.215(0.741-1.990)

0.44

HBsAg

0.776(0.421-1.431)

0.416

1.140(0.697-1.865)

0.601

AFP (ng/ml)

3.408(2.038-5.698)

< 0.001

2.088(1.499-2.909)

< 0.001

Liver cirrhosis

1.087(0.672-1.760)

0.733

1.174(0.813-1.694)

0.392

Tumor size (cm)

2.409(1.532-3.790)

< 10.001

1.806(1.311-2.488)

< 0.001

Tumor multiplicity

3.233(2.022-5.168)

< 0.001

1.972(1.429-2.722)

< 0.001

Tumor differentiation

1.649(1.246-2.183)

< 0.001

1.621(1.314-2.000)

< 0.001

Clinical stage

3.079(2.269-4.178)

< 0.001

1.785(1.457-2.187)

< 0.001

Vascular invasion

4.704(3.027-7.311)

< 0.001

2.393(1.714-3.341)

< 0.001

AZGP1

0.553(0.359-0.851)

0.007

0.706(0.513-0.972)

0.033

  1. CI, confidence interval; HR, hazard ratio; AFP, alpha-fetoprotein; HBsAg, hepatitis B surface antigen; AZGP1, zinc-alpha2-glycoprotein.