Figure 7

Impact of combined HER2 and TOP2A (HER2/TOP2A) parameters on patient outcome. Kaplan-Meier curves for combined HER2/TOP2A mRNA expression (A, B) and combined HER2/TopoIIa protein status (C, D) in terms of DFS and OS. Comparisons by log-rank test. Red lines: HER2/TOP2A high mRNA expression (A, B) or HER2/TopoIIa positive protein expression (C, D); Blue lines: all other combinations.