Fibrinogen: a novel predictor of responsiveness in metastatic melanoma patients treated with bio-chemotherapy: IMI (italian melanoma inter-group) trial

Table 3 Univariate Survival Analysis According To Laboratory Parameters

Laboratory Parameters	No. Of patients	Median Survival, Months (CI)	Odds Ratio	Log-Rank P
White Blood Count
Normal	137	12 (8.7–13.2)	1.8 (1.18–2.8)	0.0057
High	37	6 (4–10.5)
Lymphocytes
Normal	100	12 (9.5–14.8)	1.67 (1.16–2.4)	0.0049
Low	72	7.8 (6.5–10.1)
Lymphocytes (%)
Normal	118	9.1 (9.7–14.7)	2.26 (1.5–3.3)	0.0001
Low	54	5.4 (4.4–7.9)
Eosinofili
Normal	171	10 (8.2–11.9)	1.82 (0.66–5.03)	0.23
High	5	4.3 (3–15.2)
Eosinofili (%)
Normal	126	9.2 (7.8–11.6)	0.77 (0.45–1.3)	0.32
High	25	13.2 (9.5–15.4)
LDH
Normal	121	12.4 (10.5–14.6)	2.77 (1.91–4.02)	0.0001
High	55	5.4 (4.2–7)
CRP
Normal	84	10.7 (8.5–14.7)	1.80 (1.2–2.67)	0.0031
High	62	7.4 (5.1–10.4)
ESR
Normal	70	13.2 (9.5–15.5)	1.57 (1.06–2.31)	0.022
High	83	8.5 (7–10.7)
Fibrinogen
Normal	107	11.8 (9.2–14.3)	2.37 (1.58–3.54)	0.0001
High	42	5.4 (4.7–8.3)

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