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Table 3 Univariate Survival Analysis According To Laboratory Parameters

From: Fibrinogen: a novel predictor of responsiveness in metastatic melanoma patients treated with bio-chemotherapy: IMI (italian melanoma inter-group) trial

Laboratory Parameters No. Of patients Median Survival, Months (CI) Odds Ratio Log-Rank P
White Blood Count     
   Normal 137 12 (8.7–13.2) 1.8 (1.18–2.8) 0.0057
   High 37 6 (4–10.5)   
Lymphocytes     
   Normal 100 12 (9.5–14.8) 1.67 (1.16–2.4) 0.0049
   Low 72 7.8 (6.5–10.1)   
Lymphocytes (%)     
   Normal 118 9.1 (9.7–14.7) 2.26 (1.5–3.3) 0.0001
   Low 54 5.4 (4.4–7.9)   
Eosinofili     
   Normal 171 10 (8.2–11.9) 1.82 (0.66–5.03) 0.23
   High 5 4.3 (3–15.2)   
Eosinofili (%)     
   Normal 126 9.2 (7.8–11.6) 0.77 (0.45–1.3) 0.32
   High 25 13.2 (9.5–15.4)   
LDH     
   Normal 121 12.4 (10.5–14.6) 2.77 (1.91–4.02) 0.0001
   High 55 5.4 (4.2–7)   
CRP     
   Normal 84 10.7 (8.5–14.7) 1.80 (1.2–2.67) 0.0031
   High 62 7.4 (5.1–10.4)   
ESR     
   Normal 70 13.2 (9.5–15.5) 1.57 (1.06–2.31) 0.022
   High 83 8.5 (7–10.7)   
Fibrinogen     
   Normal 107 11.8 (9.2–14.3) 2.37 (1.58–3.54) 0.0001
   High 42 5.4 (4.7–8.3)