Figure 2From: Curcumin reduces expression of Bcl-2, leading to apoptosis in daunorubicin-insensitive CD34+ acute myeloid leukemia cell lines and primary sorted CD34+ acute myeloid leukemia cellsCurcumin suppressed cell growth and induced G1/S arrest. (A) Structure of curcumin. (B, C, D) KG1a, Kasumi-1 and U937 cell lines were treated with different concentrations of curcumin for 24, 48, 72, and 96 h. MTT assay was performed. (E) These three cell lines were treated with different concentrations of curcumin for 24 h and analyzed for DNA content by flow cytometry, as described in "Methods." The bar represents means ± SD of three independent experiments.Back to article page