Articles

Sort by
Previous Page Page 2 of 122 Next Page
  1. Research

    Shikonin-induced necroptosis is enhanced by the inhibition of autophagy in non-small cell lung cancer cells

    Shikonin, a natural naphthoquinone pigment purified from Lithospermum erythrorhizon, induces necroptosis in various cancer types, but the mechanisms underlying the anticancer activity of shikonin in lung cancer a...

    Hyo-Jin Kim, Ki-Eun Hwang, Do-Sim Park, Seon-Hee Oh, Hong Young Jun, Kwon-Ha Yoon, Eun-Taik Jeong, Hak-Ryul Kim and Young-Suk Kim

    Journal of Translational Medicine 2017 15:123

    Published on: 31 May 2017

  2. Research

    Aberrant monocyte responses predict and characterize dengue virus infection in individuals with severe disease

    Currently, several assays can diagnose acute dengue infection. However, none of these assays can predict the severity of the disease. Biomarkers that predicts the likelihood that a dengue patient will develop ...

    Yean K. Yong, Hong Y. Tan, Soe Hui Jen, Esaki M. Shankar, Santha K. Natkunam, Jameela Sathar, Rishya Manikam and Shamala D. Sekaran

    Journal of Translational Medicine 2017 15:121

    Published on: 31 May 2017

  3. Research

    Non-caloric sweetener provides magnetic resonance imaging contrast for cancer detection

    Image contrast enhanced by exogenous contrast agents plays a crucial role in the early detection, characterization, and determination of the precise location of cancers. Here, we investigate the feasibility of...

    Puneet Bagga, Mohammad Haris, Kevin D’Aquilla, Neil E. Wilson, Francesco M. Marincola, Mitchell D. Schnall, Hari Hariharan and Ravinder Reddy

    Journal of Translational Medicine 2017 15:119

    Published on: 30 May 2017

  4. Research

    Differential expression of microRNAs following cardiopulmonary bypass in children with congenital heart diseases

    Children with congenital heart defects (CHDs) are at high risk for myocardial failure after operative procedures with cardiopulmonary bypass (CPB). Recent studies suggest that microRNAs (miRNA) are involved in...

    Masood Abu-Halima, Martin Poryo, Nicole Ludwig, Janine Mark, Ina Marsollek, Christian Giebels, Johannes Petersen, Hans-Joachim Schäfers, Ulrich Grundmann, Thomas Pickardt, Andreas Keller, Eckart Meese and Hashim Abdul-Khaliq

    Journal of Translational Medicine 2017 15:117

    Published on: 30 May 2017

  5. Research

    Similar cardiometabolic effects of high- and moderate-intensity training among apparently healthy inactive adults: a randomized clinical trial

    Metabolic syndrome (MetS) increases the risk of morbidity and mortality from cardiovascular disease, and exercise training is an important factor in the treatment and prevention of the clinical components of M...

    Robinson Ramírez-Vélez, Alejandra Tordecilla-Sanders, Luis Andrés Téllez-T, Diana Camelo-Prieto, Paula Andrea Hernández-Quiñonez, Jorge Enrique Correa-Bautista, Antonio Garcia-Hermoso, Rodrigo Ramirez-Campillo and Mikel Izquierdo

    Journal of Translational Medicine 2017 15:118

    Published on: 30 May 2017

    The Erratum to this article has been published in Journal of Translational Medicine 2017 15:136

  6. Research

    Dendritic cells combined with tumor cells and α-galactosylceramide induce a potent, therapeutic and NK-cell dependent antitumor immunity in B cell lymphoma

    Invariant natural killer T (iNKT) cells are a small population of lymphocytes with unique specificity for glycolipid antigens presented by non-polymorphic CD1d receptor on dendritic cells (DCs). iNKT cells pla...

    Laura Escribà-Garcia, Carmen Alvarez-Fernández, Marta Tellez-Gabriel, Jorge Sierra and Javier Briones

    Journal of Translational Medicine 2017 15:115

    Published on: 26 May 2017

  7. Commentary

    The progressive fragmentation of the KIT/PDGFRA wild-type (WT) gastrointestinal stromal tumors (GIST)

    Recent advances in molecular biology have revolutionized the concept of KIT/PDGFRA wild type (WT) gastrointestinal stromal tumors (GIST) than the past. Indeed, from being defined as GIST without KIT or PDGFRA ...

    Margherita Nannini, Milena Urbini, Annalisa Astolfi, Guido Biasco and Maria A. Pantaleo

    Journal of Translational Medicine 2017 15:113

    Published on: 23 May 2017

    The Erratum to this article has been published in Journal of Translational Medicine 2017 15:125

  8. Review

    The spleen in liver cirrhosis: revisiting an old enemy with novel targets

    The spleen is a secondary lymphoid organ which can influence the progression of multiple diseases, notably liver cirrhosis. In chronic liver diseases, splenomegaly and hypersplenism can manifest following the ...

    Liang Li, Mubing Duan, Weisan Chen, An Jiang, Xiaoming Li, Jun Yang and Zongfang Li

    Journal of Translational Medicine 2017 15:111

    Published on: 23 May 2017

  9. Research

    Blood metabolomic fingerprint is distinct in healthy coronary and in stenosing or microvascular ischemic heart disease

    The endothelium is a key variable in the pathogenesis of atherosclerosis and its complications, particularly coronary artery disease (CAD). Current evidence suggests that the endothelial status can be regarded...

    Martino Deidda, Cristina Piras, Christian Cadeddu Dessalvi, Damiana Congia, Emanuela Locci, Federica Ascedu, Gianfranco De Candia, Mauro Cadeddu, Giorgio Lai, Raimondo Pirisi, Luigi Atzori and Giuseppe Mercuro

    Journal of Translational Medicine 2017 15:112

    Published on: 23 May 2017

  10. Research

    Impact of legumes and plant proteins consumption on cognitive performances in the elderly

    Numerous studies have investigated the role of the dietary factors in the prevention of cognitive decline but the short-term effects of foods choice on cognitive performances in the elderly are poorly explored...

    Elisa Mazza, Antonietta Fava, Yvelise Ferro, Marta Moraca, Stefania Rotundo, Carmela Colica, Francesco Provenzano, Rosa Terracciano, Marta Greco, Daniela Foti, Elio Gulletta, Diego Russo, Domenico Bosco, Arturo Pujia and Tiziana Montalcini

    Journal of Translational Medicine 2017 15:109

    Published on: 22 May 2017

  11. Research

    Correlation of cell-free DNA plasma concentration with severity of non-alcoholic fatty liver disease

    The assessment of fibrosis and inflammatory activity is essential to identify patients with non-alcoholic fatty liver disease (NAFLD) at risk for progressive disease. Serum markers and ultrasound-based methods...

    Thomas Karlas, Lara Weise, Stephanie Kuhn, Felix Krenzien, Matthias Mehdorn, David Petroff, Nicolas Linder, Alexander Schaudinn, Harald Busse, Volker Keim, Johann Pratschke, Johannes Wiegand, Katrin Splith and Moritz Schmelzle

    Journal of Translational Medicine 2017 15:106

    Published on: 19 May 2017

  12. Research article

    Standardization of platelet releasate products for clinical applications in cell therapy: a mathematical approach

    Standardized animal-free components are required for manufacturing cell-based medicinal products. Human platelet concentrates are sources of growth factors for cell expansion but such products are characterize...

    Francesco Agostini, Jerry Polesel, Monica Battiston, Elisabetta Lombardi, Stefania Zanolin, Alessandro Da Ponte, Giuseppe Astori, Cristina Durante and Mario Mazzucato

    Journal of Translational Medicine 2017 15:107

    Published on: 19 May 2017

  13. Research

    Bovis Bacillus Calmette–Guerin (BCG) infection induces exosomal miRNA release by human macrophages

    Tuberculosis (TB) remains a significant global health concern and its diagnosis is challenging due to the limitations in the specificity and sensitivity of the current diagnostic tests. Exosomes are bioactive ...

    Shamila D. Alipoor, Esmaeil Mortaz, Payam Tabarsi, Parissa Farnia, Mehdi Mirsaeidi, Johan Garssen, Masoud Movassaghi and Ian M. Adcock

    Journal of Translational Medicine 2017 15:105

    Published on: 12 May 2017

  14. Research

    A phase II trial of autologous dendritic cell vaccination and radiochemotherapy following fluorescence-guided surgery in newly diagnosed glioblastoma patients

    Prognosis of patients with glioblastoma multiforme (GBM) remains dismal, with median overall survival (OS) of about 15 months. It is therefore crucial to search alternative strategies that improve these result...

    Susana Inogés, Sonia Tejada, Ascensión López-Díaz de Cerio, Jaime Gállego Pérez-Larraya, Jaime Espinós, Miguel Angel Idoate, Pablo Daniel Domínguez, Reyes García de Eulate, Javier Aristu, Maurizio Bendandi, Fernando Pastor, Marta Alonso, Enrique Andreu, Felipe Prósper Cardoso and Ricardo Díez Valle

    Journal of Translational Medicine 2017 15:104

    Published on: 12 May 2017

  15. Research

    Whole blood gene expression in adolescent chronic fatigue syndrome: an exploratory cross-sectional study suggesting altered B cell differentiation and survival

    Chronic fatigue syndrome (CFS) is a prevalent and disabling condition affecting adolescents. The pathophysiology is poorly understood, but immune alterations might be an important component. This study compare...

    Chinh Bkrong Nguyen, Lene Alsøe, Jessica M. Lindvall, Dag Sulheim, Even Fagermoen, Anette Winger, Mari Kaarbø, Hilde Nilsen and Vegard Bruun Wyller

    Journal of Translational Medicine 2017 15:102

    Published on: 11 May 2017

  16. Review

    Anti-inflammatory effects of H2S during acute bacterial infection: a review

    Hydrogen sulfide (H2S), previously only considered a toxic environmental air pollutant, is now increasingly recognized as an important signaling molecule able to modulate several cellular pathways in many human t...

    Francesca Benedetti, Sabrina Curreli, Selvi Krishnan, Sergio Davinelli, Fiorenza Cocchi, Giovanni Scapagnini, Robert C. Gallo and Davide Zella

    Journal of Translational Medicine 2017 15:100

    Published on: 10 May 2017

  17. Review

    Progress of stem/progenitor cell-based therapy for retinal degeneration

    Retinal degeneration (RD), such as age-related macular degeneration (AMD) and retinitis pigmentosa, is one of the leading causes of blindness. Presently, no satisfactory therapeutic options are available for t...

    Zhimin Tang, Yi Zhang, Yuyao Wang, Dandan Zhang, Bingqiao Shen, Min Luo and Ping Gu

    Journal of Translational Medicine 2017 15:99

    Published on: 10 May 2017

  18. Research

    Experimental approach to IGF-1 therapy in CCl4-induced acute liver damage in healthy controls and mice with partial IGF-1 deficiency

    Cell necrosis, oxidative damage, and fibrogenesis are involved in cirrhosis development, a condition in which insulin-like growth factor 1 (IGF-1) levels are diminished. This study evaluates whether the exogen...

    Luis A. Morales-Garza, Juan E. Puche, Gabriel A. Aguirre, Úrsula Muñoz, Mariano García-Magariño, Rocío G. De la Garza and Inma Castilla-Cortazar

    Journal of Translational Medicine 2017 15:96

    Published on: 4 May 2017

  19. Research

    Role of estrogen receptors and Src signaling in mechanisms of bone metastasis by estrogen receptor positive breast cancers

    Evidence shows that Luminal A breast cancer is likely to undergo bone metastasis, but the mechanisms involved remain unknown. This study’s aim was to demonstrate a correlation between estrogen receptor (ER) po...

    Jen-Hwey Chiu, Che-Sheng Wen, Jir-You Wang, Chih-Yi Hsu, Yi-Fang Tsai, Shih-Chieh Hung, Ling-Ming Tseng and Yi-Ming Shyr

    Journal of Translational Medicine 2017 15:97

    Published on: 4 May 2017

Previous Page Page 2 of 122 Next Page