Volume 10 Supplement 3

7th European Workshop on Immune-Mediated Inflammatory Diseases

Meeting abstracts

Edited by Timothy Radstake, Leonie Taams and Ola Winqvist

Publication of this supplement has been supported by the conference.

7th European Workshop on Immune-Mediated Inflammatory Diseases. Go to conference site.

Noordwijk aan Zee, the Netherlands28-30 November 2012

Concatenated PDF 10S3

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Changes in nailfold videocapillaroscopy in patients with granulomatosis with polyangiitis (Wegener’s): an observational study

Authors: Julia Uceda, Rosalía Martinez, María L Velloso and José L Marenco

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P29

Content type: Poster presentation Published on: 28 November 2012
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Expression of 9G4 idiotope on autoantibodies to citrullinated peptides in patients with early inflammatory arthritis and established rheumatoid arthritis

Authors: Rita A Moura, Inmaculada de la Torre, Maria J Leandro, Jonathan CW Edwards, João E Fonseca and Geraldine Cambridge

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P30

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TRAF1/C5 locus is associated with response to anti-TNF in rheumatoid arthritis

Authors: Helena Canhão, Ana Rodrigues, Maria Jose Santos, Diana Carmona-Fernandes, José Costa, Helena Santos, Jaime Branco, Robert Plenge, Daniel Solomon, Jacome Armas, José António Silva, João Eurico Fonseca and Elizabeth Karlson

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P31

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Impaired NK and NKT cells immunobiology in rheumatoid arthritis

Authors: Ashish Aggarwal, Aman Sharma and Archana Bhatnagar

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P32

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Extrathymic Autoimmune Regulator (AIRE) expression in rheumatoid arthritis

Authors: Ae-Ri Noort, Katinka PM van Zoest, M Christina Lebre, Paul-Peter Tak and Sander W Tas

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P33

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Relative overexpression of membrane-bound versus soluble TNF in spondyloarthritis

Authors: Carmen A Ambarus, Leonie M van Duivenvoorde, Huriatul Masdar, Melissa N van Tok, Paul-Peter Tak, Nataliya G Yeremenko and Dominique L Baeten

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P34

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BAFF polymorphisms and serum levels of BAFF in Tunisian systemic lupus erythematosus patients

Authors: Nacira Laamiri, Imen Sfar, Tarak Dhaouadi, Lamia Ben Hassine, Salwa Jendoubi-Ayed, Awatef Chiha, Thouraya Ben Romdhane, Mouna Makhlouf, Taïeb Ben Abdallah, Narjess Khalfallah, Khaled Ayed and Yousr Gorgi

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P35

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Decreased expression of TSLP in labial salivary glands of patients with primary Sjögren’s syndrome is associated with local- and systemic disease parameters

Authors: Maarten R Hillen, Angela Bikker, Aike A Kruize, Marion Wenting-van Wijk, Floris PJG Lafeber, C Erik Hack, Timothy RDJ Radstake and Joel AG van Roon

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P36

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Telomere biology is differently affected within clinical subsets of systemic sclerosis and points towards different downstream defects

Authors: Jasper CA Broen, Liane McGlynn, Meng May Chee, Lenny Geurts-van Bon, Robert L Lafyatis, Timothy RDJ Radstake and Paul G Shiels

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P37

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Expression of PPARα, β, and γ in the Hartley guinea pig model of primary osteoarthritis

Authors: Fatima Ezzahra El Mansouri, Salwa Sarah Nebbaki, Nadia Zayed, Mohamed Benderdour, Johanne Martel-Pelletier, Jean-Pierre Pelletier and Hassan Fahmi

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P38

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Egr-1 mediates the suppressive effect of IL-1 on PPARγ expression in human OA chondrocytes

Authors: Salwa Sarah Nebbaki, Fatima Ezzahra El Mansouri, Nadia Zayed, Mohamed Benderdour, Johanne Martel-Pelletier, Jean-Pierre Pelletier and Hassan Fahmi

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P39

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Immunomodulatory actions of methotrexate on T cells in juvenile idiopathic arthritis

Authors: Maja Bulatović Ćalasan, Sebastiaan Vastert, Frederik Verweij, Nico Wulffraat, Femke van Wijk and Berent Prakken

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P40

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Analysis of autoantibodies against Ro52/Ro60 in patients with suspected diagnosis of autoimmune systemic disease

Authors: Iñaki Salvador, Estibaliz Ruiz-Ortiz, Alejandro Olivé, Domingo Escudero, Isabel Bielsa and Eva Martínez-Cáceres

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P41

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The effects of anti–TNF agents on the expansion of T helper-type 17 cells driven by lipopolysaccharide-stimulated monocytes

Authors: Gianluca Fossati, Louise Healy and Andrew Nesbitt

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P42

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Particularities of anaemia in framework of systemic lupus erythematosus

Authors: Elena Samohvalov, Lucia Mazur-Nicorici, Ninel Revenco and Minodora Mazur

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P43

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Prediction of treatment response by anticitrullinated protein antibodies (ACPA) levels among patients with rheumatoid arthritis

Authors: Raquel Hernández, Paz González, Alejandro Muñoz and Jose Luis Marenco

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P44

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IL-1 receptor antagonist restores IL-18 NK cell axis in systemic JIA

Authors: Sebastiaan J Vastert, Wilco De Jager, Bo Jan Noordman, Berent J Prakken and Nico M Wulffraat

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P45

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Juvenile idiopathic arthritis treated with biological therapies

Authors: Maria Luisa Velloso Feijoo, Rosalia Martinez Perez, Julia Uceda Montañes and Jose Luis Marenco de la Fuente

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P46

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Seronegative and seropositive rheumatoid arthritis treated with rituximab

Authors: Maria Luisa Velloso Feijoo, Rosalia Martínez Pérez, Lucia González Mayordomo and Jose Luis Marenco de la Fuente

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P47

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NAMPT/Visfatin expression by inflammatory monocytes mediates arthritis pathogenesis by promoting IL-17–producing T cells

Authors: Jessy Présumey, Gabriel Courties, Pascale Louis-Plence, Virginie Escriou, Daniel Scherman, Yves-Marie Pers, Hans Yssel, Jérôme Pène, Diego Kyburz, Steffen Gay, Christian Jorgensen and Florence Apparailly

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P48

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TNF-inhibitor drugs regulate human pathogenic Th17 cells through induction of IL-10

Authors: Hayley G Evans, Nicola J Gullick, Gina J Walter, Urmas Roostalu, Klaus S Frederiksen, Jens G Gerwien, Andrew P Cope, Frederic Geissmann, Bruce W Kirkham and Leonie S Taams

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P49

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Wegener granulomatosis: type of presentation and initial treatment in a series of 23 cases

Authors: Rosalia Martínez-Pérez, Mario Leon, Julia Uceda, S Rodriguez Montero, A Muñoz, ML Velloso and JL Marenco

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P50

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Clinical and economic efficiency to reduce dose etanercept and adalimumab in patients with rheumatoid arthritis

Authors: Rosalía Martínez-Pérez, Sergio Rodríguez-Montero, Alejandro Muñoz, Julia Uceda, Mario León, Francisco Gallo, Maria Luisa Velloso and José Luis Marenco

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P51

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Response measures influence comparative effectiveness of biological drugs in rheumatoid arthritis

Authors: Helena Canhao, Vasco Romao, Fernando Martins and Joao Eurico Fonseca

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P52

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HLA and non-HLA genes in Behçet’s disease: a multicentric study in the Spanish population

Authors: Marco Antonio Montes-Cano, Marta Conde-Jaldon, Jose Raul Garcia-Lozano, Lourdes Ortiz-Fernandez and Maria Francisca Gonzalez-Escribano

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P53

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MicroRNAs underlie plasmacytoid dentritic cell dysfunction in systemic sclerosis

Authors: Jasper C Broen, Lenny van Bon, Nick P Rossen, Marzia Rossato and Timothy RDJ Radstake

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P54

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Inducible Treg cell populations as cell based-therapy for rheumatoid arthritis

Authors: Delphine Martire, Julie Quentin, Anne-Laure Mausset-Bonnefont, Hélène Asnagli, Nathalie Belmonte, Arnaud Foussat, Christian Jorgensen and Pascale Louis-Plence

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P55

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LPS-induced gene expression of inflammation-related genes in neutrophils from familial Mediterranean fever patients

Authors: Gayane Manukyan, Eva Kriegova, Anush Martirosyan, Regina Fillerova, Maretta Tatyan and Martin Petrek

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P56

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Isolated anti-Ku antibody in scleroderma-myositis overlap syndrome: the histo-pathological patern

Authors: Bernard Azanmene, Valerie Badot, Severine Verlinden, Maria Josee Fernandez-Lopez, Hazim Kadhim, Francis Corazza, Wolfram Fink, Anne Peretz and Jacques Bentin

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P57

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Autoimmunity and cystatin SA 1 deficiency behind chronic mucocutaneous candidiasis in autoimmune polyendocrine syndrome

Authors: Emma Lindh, Johan Brännström, Petra Jones, Fredrik Wermeling, Signe Hässler, Corrado Betterle, Ben Zion Garty, Mats Stridsberg, Björn Herrmann, Mikael CI Karlsson and Ola Winqvist

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P58

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A phenotypic, transcriptional and TCR Vβ repertoire signature of CD8+ T cells define a population at-risk of long-term kidney graft dysfunction

Authors: Nicolas Degauque, Françoise Boeffard, Annaick Pallier, Richard Danger, Magali Giral, Jacques Dantal, Yohann Foucher, Cécile Guillot-Gueguen, Jean-Paul Soulillou and Sophie Brouard

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P59

Content type: Poster presentation Published on: 28 November 2012
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Control of transplant tolerance and intragraft regulatory T cell localization by CCL5

Authors: Nahzli Dilek, Nicolas Poirier, Claire Usal, Bernard Martinet, Gilles Blancho and Bernard Vanhove

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P60

Content type: Poster presentation Published on: 28 November 2012
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Evaluation of FR104, a Treg sparing antagonist anti-CD28 monovalent Fab’ antibody in kidney transplantation in non-human primates

Authors: Nicolas Poirier, Nahzli Dilek, Caroline Mary, Jeremy Hervouet, David Minault, Julien Branchereau, Xavier Tillou, Stephanie Le Bas-Bernardet, Bernard Vanhove and Gilles Blancho

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P61

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Inhibition of cystathionine-γ-lyase controls interleukin-12 production by dendritic cells, delayed-type hypersensitivity and transplant rejection

Authors: Romain Vuillefroy de Silly, Flora Coulon, Nicolas Poirier, Vojislav Jovanovic, Sophie Brouard, Véronique Ferchaud-Roucher, Gilles Blancho and Bernard Vanhove

Citation: Journal of Translational Medicine 2012 10(Suppl 3):P62

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7th European Workshop on Immune-Mediated Inflammatory Diseases

Meeting abstracts

Changes in nailfold videocapillaroscopy in patients with granulomatosis with polyangiitis (Wegener’s): an observational study

Expression of 9G4 idiotope on autoantibodies to citrullinated peptides in patients with early inflammatory arthritis and established rheumatoid arthritis

TRAF1/C5 locus is associated with response to anti-TNF in rheumatoid arthritis

Impaired NK and NKT cells immunobiology in rheumatoid arthritis

Extrathymic Autoimmune Regulator (AIRE) expression in rheumatoid arthritis

Relative overexpression of membrane-bound versus soluble TNF in spondyloarthritis

BAFF polymorphisms and serum levels of BAFF in Tunisian systemic lupus erythematosus patients

Decreased expression of TSLP in labial salivary glands of patients with primary Sjögren’s syndrome is associated with local- and systemic disease parameters

Telomere biology is differently affected within clinical subsets of systemic sclerosis and points towards different downstream defects

Expression of PPARα, β, and γ in the Hartley guinea pig model of primary osteoarthritis

Egr-1 mediates the suppressive effect of IL-1 on PPARγ expression in human OA chondrocytes

Immunomodulatory actions of methotrexate on T cells in juvenile idiopathic arthritis

Analysis of autoantibodies against Ro52/Ro60 in patients with suspected diagnosis of autoimmune systemic disease

The effects of anti–TNF agents on the expansion of T helper-type 17 cells driven by lipopolysaccharide-stimulated monocytes

Particularities of anaemia in framework of systemic lupus erythematosus

Prediction of treatment response by anticitrullinated protein antibodies (ACPA) levels among patients with rheumatoid arthritis

IL-1 receptor antagonist restores IL-18 NK cell axis in systemic JIA

Juvenile idiopathic arthritis treated with biological therapies

Seronegative and seropositive rheumatoid arthritis treated with rituximab

NAMPT/Visfatin expression by inflammatory monocytes mediates arthritis pathogenesis by promoting IL-17–producing T cells

TNF-inhibitor drugs regulate human pathogenic Th17 cells through induction of IL-10

Wegener granulomatosis: type of presentation and initial treatment in a series of 23 cases

Clinical and economic efficiency to reduce dose etanercept and adalimumab in patients with rheumatoid arthritis

Response measures influence comparative effectiveness of biological drugs in rheumatoid arthritis

HLA and non-HLA genes in Behçet’s disease: a multicentric study in the Spanish population

MicroRNAs underlie plasmacytoid dentritic cell dysfunction in systemic sclerosis

Inducible Treg cell populations as cell based-therapy for rheumatoid arthritis

LPS-induced gene expression of inflammation-related genes in neutrophils from familial Mediterranean fever patients

Isolated anti-Ku antibody in scleroderma-myositis overlap syndrome: the histo-pathological patern

Autoimmunity and cystatin SA 1 deficiency behind chronic mucocutaneous candidiasis in autoimmune polyendocrine syndrome

A phenotypic, transcriptional and TCR Vβ repertoire signature of CD8+ T cells define a population at-risk of long-term kidney graft dysfunction

Control of transplant tolerance and intragraft regulatory T cell localization by CCL5

Evaluation of FR104, a Treg sparing antagonist anti-CD28 monovalent Fab’ antibody in kidney transplantation in non-human primates

Inhibition of cystathionine-γ-lyase controls interleukin-12 production by dendritic cells, delayed-type hypersensitivity and transplant rejection

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